REJEON PCL Whakakii Injection Anti-wrinkle hiki me te whakau
Ko te Taketake o REJEON PCL
I roto i nga tau 20 kua pahure ake nei, kua tino pai ake to maatau mohiotanga ki tetahi o nga waahanga tino uaua o te tinana o te tangata – te kanohi – me te maha o nga hanganga tinana hou kua kitea.
I te wa ano, he plethora o kore-haparapara
kua waatea nga tikanga mo te rongoa
nga tohu o te koroheketanga me te whakaora i te taiohi
ahua o te mata. Ko REJEON te tuatahi, a
I tenei wa anake, ko te collagen sti mulator he mea hanga mai i nga microspheres polycaprolactone, e whai hua ana ki ona whakanikotanga rerehua roa. REJEON
Ko nga ahuatanga ahurei o te tikanga he whiringa pai mo te whānuitanga o nga tikanga o te kiko ngohengohe.
Whakarāpopototanga
Ko te titonga o REJ EO N ,
7 0 % CMC-wai-wai
kawe reeraa3 0 % PCL
titonga,whakaaetia mo
he pānga whakakī tonu
na te CMC, ka whai i te whakaihiihi o te tinana ake collagen (neocollagenesis) .
Ko te CMC he 2 ki te toru
marama i muri i te werohangaka whakakapihia e te ake o te manawanui
collagen ( te nuinga o te momo I) i whakaongaongatia e
PCL moroiti. Ko nga microspheres o te PCL he bioresorbable hoki.
He maha nga huanga a REJEON ka waiho hei whiringa ataahua hei whakakii kiri:
①Ko te whakaurunga o nga microspheres polymer, i roto i te 1 marama, me te scaffold collagen e pa ana ki te aukati i etahi atu tauhohenga mumura kei puta13
②Ko te momo collagen e mau tonu ana i roto i te waahi werohia ko te nuinga ko te 'maamaa' collagen scaffold o collagen momo I5
a) Ko te whakahekenga o te momo collagen III te tikanga kaore he whakaongaonga ake o te urupare inflammatory
③Ko te whakahekenga o nga mea whakauru REJEON ka oti i te hauwai, ka waiho ko te wai me te hauhaa.
④Na te mea he nui ake te rōrahi whakamutunga i roto i te wāhi rongoa i te rōrahi o Ellansé i werohia, karekau he hiahia ki te 'pa atu' ki te maimoatanga
a) He nui ake te rōrahi whakamutunga i te rōrahi i werohia e te 20–30% nā te hanganga o ngā muka collagen momo I11
⑤Ko te waatea o nga putanga e rua o REJEON he rereke te roa o te mahi, ko te tikanga ko te roa o te paanga maimoatanga ka taea te whakarite ki te manawanui o te manawanui.
whakaritenga
a) Ka tutuki tenei ma te rereke i te roa o nga mekameka PCL, ka taea te matapae, te whakahaere me te whakarite koiora.
⑥He rite tonu te tikanga maimoatanga ahakoa te hua REJEON i tohua a) He rite tonu:
● Ngā āhuatanga Rheological
● Hangarau
● Pūwero
● Te ngira/cannula
REJEON PCL Hanga ahurei
Ko REJEON PCL he mea tito he ahurei, he arai
whakakotahitanga o:
● 7 0 % carboxymethyl cellulose (CMC) - kaikawe reera
● 3 0 % polycaprolactone (PCL) microspheres (Whakaahua 1.4) 3, 4, 5
Ko nga microspheres PCL kei roto
whakatārewatanga ōrite i roto i te CMC-e hāngai ana te kawe rā. Ko te PCL me te CMC he pai rawa atu, kua whakamatauhia hoki te ahua koiora.
REJEON PCL rauemi mata i ahu mai i Gemany
PCL MICROSPHERES
Ko te PCL he polyester hauora kore paitini, i whakahiato tuatahi i te timatanga o te 1930s4, ara.
he ataahua mo te whakamahi i roto i nga whakakii kiri na te ngawari o te koiora; ka whakamarohia ki roto i te warowaiha me te wai i roto i te tinana5.
Ko nga microspheres PCL e whakamahia ana i roto i
Ko RE JEON i hangaia hei tuku
tino pai te paioraora6. He mata maeneene to ratou, a
te hanga porohita me te rahi o
āhua 25–50 μm
He pai rawa te ahua o te PCL mo te haumarutanga3 kua whakamahia i roto i te mara rongoa koiora mo te neke atu i te 70 tau mo te maha o nga tono, mai i te tui ki te kiko me te okana hei whakakapi ma te taa 3D (Whakaahua 1.6)4. Kei te whakamahia hoki i roto i te tohu-CE me te US Food me
Drug Administration (FDA)- nga hua kua whakaaetia.
Nga taonga o CMC
Ko te CMC he mea taiao i ahu mai i te cellulose; ehara i te hono-whakawhiti, he kore paitini. Ko etahi atu o ona taonga ko (Whakaahua 1.7)4 :
● He rongoa rongoa rongonui
● He hygroscopic
● Kua tohua e te FDA e mohiotia ana he haumaru ( GRAS)
● Ka puta te resorption i roto i te 2 – 3 marama
Ko nga painga matua o REJEON PCL Filler
Ko REJEON PCL he moroiti ahurei me te tino pai, me te rahi o te matūriki e tutuki ana ki nga paerewa haumaru o te ao me te mata maeneene e taea ai te whakatairanga tonu i te tipu o te collagen.
Whakatairanga Collagen na REJEON:He taunakitanga Scientific
Kua REJEON
whakamatauria i roto i te kararehe
tauira i werohia nga rapeti
ko REJEON S
(PCL-1) ranei REJEON M (PCL-2) hei tirotiro i te neocollagenesis5 .
E iwa marama i muri i te werohanga o te PCL-1,
kua puta te neocollagenesis me nga microspheres PCL o PCL- 1 kua tino resorbed (Whakaahua 1. 1 1) 5.
I tenei wa, me te PCL-2 i te 9 marama,
he taunakitanga o te hanganga o
momo I me momo III collagen huri noa
PCL moroiti. I te 2 1 marama i muri i te werohanga, kei te noho tonu nga microspheres PCL-2 i roto i te kiko i werohia5.
I roto i te rangahau pairati mo RE JEO N i roto i te tangata, i whakauruhia nga turoro ki te tango i a Ellansé i werohia ki roto ki te temepara.
rohe9 . Ko te tātaritanga hitori o te kiko i puta mai i nga koiora kua kitea
te hanga collagen huri noa i nga matūriki PCL i werohia (Whakaahua 1. 12) 9, e tautoko ana i nga kitenga rite i whakaatuhia i mua
kiko rapeti5.
REJEON tikanga mahi
E rua nga wahanga mahi a REJEON (Whakaahua 1.9)1,4 :
● Hipanga 1: I muri tonu i te werohanga, ka whakaratohia e te waahanga CMC te rōrahi rangitahi,
ka heke haere mo te 2-3 marama
● Hipanga 2: Ko nga microspheres PCL ka kuhu
neocollagenesis o te momo I me te III collagen, me te tohe tonu momo I collagen
ka piki haere te hanganga i roto i te 1 – 3 marama me nga microspheres PCL
ka uru ki roto i te momo I collagen
paparanga. Ko te rōrahi collagen ka puta
ka whakakapi i te pikinga o te rōrahi tuatahi na te CMC gel
Ko te scaffold collagen i whakahihikohia e te PCL
ka mau tonu te microspheres i muri i te resorbed, ka piki ake te roa o te rōrahi ka kitea me REJEON
He pai nga hua o REJEON PCL Filler
Ko te REJEON PCL Filler he kaihoko whakakī roa teitei ka taea te maeneene i nga tohu i mahue i te waa me te whakahoki ano i te ahua moata me te taiohi ki te kanohi.
REJEON PCL FILLER WHAKAARO KOREUTU
E hiahia ana matou ki te whakapuaki i o maatau tohungatanga me
te matauranga mo te wa me te pehea te whakauru i te r eon i roto i nga mahi haumanu. Te ti'aturi nei au ka whai hua te kaipanui i te ahua ano o tana mahi ki ahau mo nga tau 10 kua pahure ake nei: te tuku maimoatanga haumaru me te pai ake o nga hua me nga hua roa. Ko RE JEON he taputapu taketake i roto i aku mahi, a kua pai ake ahau ki te injector! ”
Takuta Francisco de Melo
Taonga Kirihou, UAE
“ Ko RE JEON taku tino whakakī kiri
7 tau. Ma tenei pukapuka ka awhina koe ki te mohio ki te whakamahi
RE JEON a ka aroha koe ki a ia. ”
Takuta Shang- Li Lin
Kairangahau, Taiwana
"Ko te whakapai ake i te hanganga me te kiri
te kounga ka puta mai i te ahurei a RE JOE N
Ko te neocollagenesis kaore e rite. Ko te kore rawa ko tetahi o nga taputapu pai rawa atu mo nga whare haumanu e hiahia ana ki te whai hua me te haumaru i roto i te hua injectable. Kei a REJ EO N te
te kaha ki te whakarato i te aranga roa me te whakaniko i te hanganga kanohi me te wa kotahi noa. ”
Dr Ingrid Ló pez- Gehrke
He tohunga kiri kiri, Mexico
" He tino harikoa ahau ki te whakamahi i a RE JEON na te mea whakamiharo o te waiata waiata. Ma tenei ka iti ake
hua hei whakamahi, a na roto i te hanga tuturu o te momo collagen I, he tino kaha mo te kiri
whakahounga. He maha nga turoro e kii mai ana: ' Ko te wa tuatahi tenei
He mea mau tonu taku', 'Tirohia te kounga o toku kiri'. Tino taku whakakī tino pai. ”
Takuta Pierre Nicolau
Takuta Kirihou, Spain
REJEON MAJOR MILESTONES
Whai muri i te rangahau me te whanaketanga, me te haumanu
te whakamatautau, i whiwhi a REJEON i te tiwhikete ISO 13485 Whakahaere Kounga i roto
20081 (Whakaahua 1.2). I te tau 2009, ko te tohu Whakaaetanga a te Pakeha (CE).
tuku, arahi
ki te whakarewanga tino angitu o
te hua i roto i te UK, Germany me Spain. I muri mai etahi atu whakarewatanga, neke atu i te 69 nga rehitatanga
whenua e 2018. Hei 2019, te
10-tau huritau o rejeon, atu
neke atu i te 1 miriona nga syringe kua hokona
huri noa i te ao. Engari kaore te korero angitu i mutu i reira, me te waahi hangahanga hou i Netherlands ka timata
hanga i te 2020
REJEON PCL PRODUCT Taipitopito
1ml/wahi
Whakaaetia te taakete OEM
